Answer:
The correct insulin pathway is described as under:
2. Binding of insulin to the alpha subunit of the insulin receptor
8. Activation of insulin receptor tyrosine kinase
3. Phosphorylation of IRS proteins
6. Phosphorylation of phosphinositide 3-kinase (PI-3K)
4. Conversion of PIP2 to PIP3
7. Activation of PIP3-dependent protein kinase B (PDK1)
5. Glut4 receptors transported to the cell membrane
Explanation:
The insulin signaling pathway is described as under:
RTK (receptor tyrosine kinases) which is a receptor for insulin is an extracellular receptor but in contrast to other cell surface receptors it is catalytic in nature. In the absence of insulin (ligand), it is monomeric but as soon as it gets activated (activation occurs upon ligand binding), it undergo dimerization. It leads to auto-phosphorylation in it's tyrosine residue which subsequently leads to phosphorylation of tyrosine residue of other receptors. Such hyper-phosphorylated receptor have high affinity with enzyme/molecule like IRS protein which have SH2 domain . IRS down stream activates phosphinositide 3-kinase (PI-3K). This enzyme converts component of animal cell membrane PIP2 into PIP3. PIP3 also remains membrane bound but it has the potential to phosphorylate another enzyme named as PIP3-dependent protein kinase B (PDK1). Further, PDK1 leads to the activation of Akt or PK-B. Akt is a serine-threonine kinase which ultimately leads to the recruitment of Glut4 receptors on cell membrane for uptake of more and more glucose into the cell.
Note: Apart from this Akt also phosphorylates another protein named as FOXO which ultimately causes cell growth, Akt can also phosphorylate BAD protein so as to restrict cell apoptosis or we can say it leads to cell survival, Akt also leads to translation in a cell with the help of mTOR raptor etc.
Answer:
<em>The correct option is c) the vegetable group contains legumes, which can be counted as protein foods.</em>
Explanation:
The USDA Food Patterns were formulated so that people could be helped in carrying out Dietary Guidelines recommendations. These Guidelines help people understand and identify the daily food which they shall consume. There are three basic lifestyles of diet which these guidelines describes:
1) The Healthy U.S.-Style Pattern
2) the Healthy Vegetarian Pattern
3) Healthy Mediterranean-Style Pattern
These guidelines also describe that legumes are an excellent food which shall be consumed by all vegetarians as they are an excellent source of proteins.
Answer: true
Explanation: In gel electrophoresis, the smaller the size/molecular weight of DNA the faster it moves across the gel and vise versa. This is as a result of the pore size of the gel which is usually prepared 1g of agarose in 100ml of distilled water. So a DNA fragment with 1000 base pairs will "struggle" its movement across the gel pore making it mive less faster and further. Movement and molecular weight of DNA are inversely proportional.
