A comma is required to set apart an introductory phrase from the rest of the sentence. This comma is sometimes optional if the introductory phrase is less than four words long. Some examples of introductory phrases include "before the movie starts" and "while getting ready for the play."
Machiavelli uses reasoning and an example as evidence in an argumentative structure to support his claim that a prince must destroy a city that is accustomed to freedom if he wants to hold it.
personally i think it is "rootless" as wanderers don't really have family roots in a town or any certain town that they live in because the are travellers.