Answer:
1. CGAGGTT → CGTT (Deletion)
2. ATTCGG → ATTCGGATTCGG (Duplication)
3. CTTAAT → TAATTC (Inversion)
4. CTTAAT → CTTAACGCT (Insertion)
5. CGAT → CTAT (Substitution)
6. CCGGTT + TTAGGC = CCGTTA + GTTGGC (Translocation)
Explanation:
1. CGAGGTT → CGTT (Deletion) ---- This is called deletion because it involves the removal of 3 base pairs (AGG) from the DNA sequence.
2. ATTCGG → ATTCGGATTCGG (Duplication) ---- In this case, the particular sequence (ATTCGG) is copied again or duplicated.
3. CTTAAT → TAATTC (Inversion)----- This is called inversion mutation because the DNA sequence breaks off and is reattached but this time in a reverse order i.e. CTT becomes TTC, placing the last base first and the first base last.
4. CTTAAT → CTTAACGCT (Insertion) ------ This is called insertion mutation because it involves the addition of extra base pairs (CGC) into the sequence. The Insertion occurs between the last A and T nucleotide.
5. CGAT → CTAT (Substitution) ----- This is called substitution because Guanine base is replaced by Thymine in the DNA sequence. It is specifically called a transversion substitution because a purine (Guanine) is replaced by a pyrimidine (Thymine). It is called a point mutation because it involves a single base.
6. CCGGTT + TTAGGC = CCGTTA + GTTGGC (Translocation) ----- in this case, CCGGTT and TTAGGC are sequences on different chromosomes. Portions of sequence on the first chromosome (GTT) and second chromosome (TTA) breaks off and gets reattached/exchanged in each other i.e. the first chromosome gets TTA while the second gets GTT. This kind of mutation is called translocation.
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Accuracy describes how well a measuring instrument determines the variable it is measuring. How close the value is to real value. The level of accuracy of measuring tool determines the detail to which it can measure. In order to be accurate in their work scientists need first select a measuring instrument that allows an appropriate measure of accuracy and then to calibrate it. Calibrating an instrument involves measuring already known quantities to check how accurately it is. In the laboratory accuracy of a test is determined when possible comparing results from the test in question with results geenrated from an established reference method.
