Question

Given that the sequence of nucleotides in a DNA strand will be used to produce an mRNA strand that will then code for a protein, mutations in the DNA can affect the final product. Depending on the severity of the mutation, the protein can range from not being affected to being rendered completely nonfunctional, especially if the reading frame is altered. Which of the following represents a change in reading frame if the template strand of DNA reads as follows?
A) AGCTGGACTTTAGACAAG
B) AGCTGGACTTTAGACAAG
C) AGCTGGACTTGAGTGAACAAG
D) AGCTGGACTATAGACAAG
E) AGCUGGACUUUAGACAAG
F) AGCTGCGACTTTAGACAAG

Answer 1

Answer:

AGCTGCGACTTTAGACAAG

Explanation:

The response is AGCTGCGACTTTAGACAAG because this mutation has a number of nucleotides that is not multiple of three bases for codon, which is required for the synthesis of amino acids. In consequence, this mutation will change the reading frame in which ribosome reads the sequence of the mRNA