1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Softa [21]
3 years ago
13

Why are microdeletions and microinsertions difficult to diagnosis using karyotyping?

Biology
2 answers:
Harman [31]3 years ago
8 0
Because only the chromosomes can be seen in a karyotype, and microdeletions or insertions are mutations at the molecular level, it is virtually impossible to detect such mutations at the chromosomal level. 
MrRa [10]3 years ago
7 0

Answer & explanation:

Mutations that occur by microinsertions or microdeletions (usually a pair of nitrogenous bases) can result in a change in the reading phase of the gene, completely modifying its translation into a particular protein.

Microinsertions are responsible for inserting a nucleotide into the DNA sequence, while microdeletions remove a nucleotide from the DNA sequence.

Diagnosing microdeletions or microinserts is highly difficult and requires highly skilled professionals, since many of the detected changes represent variations in copy number without clinical significance or of unknown clinical significance.

You might be interested in
explain how a mutation is an individuals DNA occurs, and describe the effect it may have on the individuals trait. I need help o
Mazyrski [523]
Mutations are spontaneous and occur at random however there are some mutagenic agents which increase the chance of this happening such as radiation exposure. If it is a point shift mutation then only a few bases on the dna sequence are changed so only changes a few of the amino acids in that chain (such as inversion of a base). If its a frame shift then the base sequence is altered so much so that every amino acid from after that changes (such as deletion of a base) which can create things such as cri-du-chat syndrome which results from a piece of chromosome 5 is missing. Hope this helps:)
4 0
3 years ago
The physician is attending to a 72-year-old client with a malignant brain tumor. the physician recommends immediate radiation th
MariettaO [177]
Physician recommends radiation therapy because radiation therapy helps in preventing cellular growth. It uses high-energy radiation to shrink tumor or kill cancer cells. It may be used to cure or to control malignancy when the tumor can no longer be removed or when lymph node involvement is present; also, it can be used prophylactically to prevent spread. Radiation therapy kills cancer cells by damaging their DNA which is the molecules inside cells that carry genetic information and pass it from generation to generation. Radiation therapy can either damage DNA directly or create charged particles within the cells that can in turn damage the DNA. Cancer cells whose DNA is damaged beyond repair stop dividing or die and when these cells die, they are eliminated by the body through natural process.
3 0
3 years ago
How does pressure relate to force
stepladder [879]

Answer:

Pressure is simply the force experienced by an object divided by the area of the surface on which the force acts. Note that the force here is the force acting perpendicular to the surface. The unit for pressure is the pascal, Pa.

Explanation:

8 0
3 years ago
Iron Ore Crystal Shape
Agata [3.3K]
Hematite is a mineral that is made of Iron and Ore and has a Crystal Shape.
6 0
3 years ago
Your friend just spent a day at the beach but forgot to use sunscreen. That evening, she complains of a great deal of pain, and
iVinArrow [24]
Answer: Your friend has suffered a Second Degree burn.
3 0
4 years ago
Other questions:
  • How is a country's income related to its ecological impact
    15·1 answer
  • If a cube measures 2.2cm, what is its volume?
    6·1 answer
  • It has been discovered that this type of cell is found in humans and is more numerous in humans than there are human cells thems
    11·2 answers
  • The specialized soft tissue manipulation technique used to ease the pain of conditions such as fibromyalgia, movement restrictio
    13·1 answer
  • Two chromosomes that are similar but not identical are called _______________________. When the chromosomes are duplicated, two
    8·1 answer
  • Plz help i will give u BRAINLIEST
    10·1 answer
  • Why must digestion happen before absorption can take place?
    14·2 answers
  • When once- ler factory closed, what happened to the town?<br> It’s from the movie The Lorax
    14·1 answer
  • Which statement is an accurate description of genes? A) Proteins are made of genes and code for DNA B) Genes are made of protein
    8·1 answer
  • HELP me, please!!!
    15·2 answers
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!