Well, timbre is related with the envelope of the acoustic wave. The form of the wave will be received by your ear and then translated to electrical impulses to your brain. I think, that we are adapted to consider "continuous and smooth waveforms" as "nice", so timbre will be one of the first characteristics that your brain will analyze.
This means “used to identify a specific person or thing close at hand or being indicated or experienced.”
It is The art of producing decorative handwriting or lettering with a pen or brush, it was used on many occasions to write important letters and sayings.
