It could be north and south or the Earths axis
http://1kai.dokkyomed.ac.jp/mammal/en/genus_list.html
Facilitated diffusion. It is a passive transport mechanism in which carrier proteins shuttle molecules across the cell membrane without using the cell’s energy supplies. Instead, the energy is provide by the concentration gradient, which means that molecules are transported from higher to lower concentrations, into or out of the cell. The carrier proteins bind to glucose, which causes them to change shape and translocate the glucose from one side of the membrane to the other. Red blood cells use facilitated diffusion to absorb glucose.
In a reading frame, one base is misplaced for another.
But in a frameshift mutation, a base is added or removed.
Remember, codons are groups of three, and they code for amino acids. In frameshift mutations, another base is added and that completely shifts the frame. Hence, the amino acids are messed up, and so is the protein made from it.
