Answer:Smallpox and vaccination are intimately connected. Edward Jenner developed the first vaccine to prevent smallpox infections, and this success led to the global eradication of smallpox and the development of many more life-saving vaccines.
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They were not happy about it and would always have to watch what they were saying.
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A. They contributed to the increasing reliance of Virginia and Maryland on African Slave labor.
After America was established, were similar to multiple eras with migration. Firstly, there was a language barrier. Many immigrants during that time had no knowledge of speaking English. If the immigrant had no body to rely on, like friends or family, they would be said to handicapped. Of course, many Americans highly disliked immigrants. The Americans didn't like immigrants because they felt like they took their jobs away from them, and did not respect their American traditions.