Question

One of the causes of morbidity for the Zika Virus is Guillain-Barré Syndrome, an immune attack of nerve cells. One possible mechanism for this is the virus's interference with normal immune function. In HIV the virus uses the CD4 receptor to enter T-cells. To assess if this might be a possibility in Zika infections BLAST the CD4 Reference Sequence (NG_027688.1) against the Zika Virus (taxid:64320) with blastn (select all that apply):
A. None of the recovered sequences have identities of greater than 80%.
B. Multiple Zika virus isolates are observed to have E-values of less than 0.02.
C. High scoring BLAST hits are observed in Zika virus isolates from humans, mosquitoes, and monkeys.
D. The BLAST hits returns a synthetic construct that is a 1947 Zika Virus rescued with a CMV promoter driven cDNA clone.

Answer 1

Answer:

Option- B

• High scoring BLAST hits are observed in Zika virus isolates from humans, mosquitoes, and monkeys.

• One of the causes of morbidity for the Zika Virus is Guillain-Barré Syndrome, an immune attack of nerve cells. One possible mechanism for this is the virus's interference with normal immune function. In HIV the virus uses the CD4 receptor to enter T-cells. To assess if this might be a possibility in Zika infections BLAST the CD4 Reference Sequence (NG_027688.1) against the Zika Virus (taxid:64320) with blastn (select all that apply), high scoring BLAST hits are observed in Zika virus isolates from humans, mosquitoes, and monkeys.