The correct answer is A) France and England.
The two countries with land claims on the Mississippi River were France and England.
In colonial America times, European superpowers such as France and England had many territorial interests and wanted to control different regions of the North American territories. This created so much conflict and was the main cause of the French Indian War that started in 1754 and ended in 1763.
The British allied with Native American tribes such as the Iroquois, Cherokee, and Catawba. The French Allied with Indian tribes such as the Lenape, Algonquin, the Ottawas, and the Wabanaki Confederacy.
