Hormones glucagon and insulin are produced in the alpha and beta cells respectively in the Islet of Langerhan in the pancreas. They are involved in the negative feedback system of blood glucose regulation in homeostasis.
GLUCAGON: when there is a low blood glucose concentration, the pancreas detect this and alpha cells produce and release glucagon. Glucagon causes the cells of the body to absorb less glucose from the blood. It also inhibits the process of converting glucose into glycogen (glycogenesis) and cause gluconeogenesis (process of converting amino acids/proteins and lipids/fats into glucose) and glycogenolysis (conversion of glycogen to glucose). Finally, glucagon decreases the rate of respiration so less glucose is required.
INSULIN: when blood glucose is high, insulin is released. Insulin binds with cell surface receptors of cells and activates the enzymes attached to the receptor. The enzymes cause a conformational change in the structural proteins that surround glucose transport protein containing vesicles, causing them to move out of the way so the vesicles migrate up to the cell membrane and glucose transport proteins can fuse with it. Thus, more glucose can be taken in by cells. Insulin also cause glycogenesis (converting glucose into glycogen) and inhibits gluconeogenesis and glycogenolysis.
Basically insulin decreases blood glucose concentration (eg. after eating) and glucagon increases it (eg. skipping breakfast in the morning)
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The answer is apex and base. To simplify, the apex of the heart rests on the diaphragm and from its base, the great vessels emerge. In addition, blood vessels that are nearer to the pumping heart and must enlarge to endure pressure variations are named elastic arteries and foramen ovale permits blood to pass from the right to the left atrium, therefore avoiding to pass the fetal lungs.
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Answer:
1. Today instead of rotating upright, The earth's axis is tilted 23.5 degrees. The angle varies a little over time, but the gravitational pull of the moon prevents it from shifting by more than a degree so. This tilt is what gives us seasons.
2.The cooling effects of more indirect sunlight cause autumn and winter. Because of the earth's approximately 23.5° tilt, the season in the northern and southern hemispheres reversed, about six months apart from each other.
