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Firdavs [7]
3 years ago
13

The gene for cystic fibrosis is a recessive trait. this disorder causes the body cells to secrste large amounts of mucus that ca

n damage the lungs, liver, and pancreas. if one out of 20 people is a carrier of this disorder, why is only one out of 1,600 babies born with cystic fibrosis?
HELP PLEASE
Biology
1 answer:
Iteru [2.4K]3 years ago
3 0
The reason this is so different is because those that are carriers (1 in 20) are heterozygous and to have a child with CF, they have to have a child with another carrier and then have the unlucky occurrence that their child will end up homozygous recessive.

So, 2 parents are Cc
C= normal CFTR (the gene at question here - Cystic Fibrosis Transmembrane Receptor)
c = mutated CFTR

Cross: Cc x Cc
You get: CC (1); Cc (2) and cc (1)....there is only a 0.25 chance that each time you have a child that it will be diseased (cc). Highest chance that the child is a carrier (Cc - 0.50) and similar low chance to no longer carry the recessive damaged allele (CC - 0.25)
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