I would say technology? New medicines.
It began with a dispute over control of the confluence of the Allegheny River and Monongahela River called the Forks of the Ohio, and the site of the French Fort Duquesne in Pittsburgh, Pennsylvania.
Alexander the great used religion to inspire people, they would be loyal to him.
It is Containment. I hope this helps.
The Populist Party was important in United States history because it proposed ideas that later became law