Hernando de Soto discovered the Mississippi River in 1541. Hope this helps! :)
The Slave Coast is a historical name formerly used for parts of coastal West Africa along the Bight of Benin. The name is derived from the fact that it was a major source of African slaves during the Atlantic slave trade from the early 16th century to the 19th century.
I'm pretty sure it was the horse bc native americans no longer traveled on foot for long distances. instead, they had the ability to travel using horses which was faster and more efficient