Answer: Environmental racism
Explanation:
Environmental racism is the process whereby, communities with poorer people and also has no political backup are been expose or experience unjust and disproportionately heavy exposure of poor and toxic chemicals, contaminated air and water, unsafe workplaces, and other environmental hazrd. Environmental racism is highly associated with factors that link poverty to poor health, including inadequate access to medical and preventive care, lack of safe play spaces for children, lack of access to healthful foods, absence of good jobs, crime, and violence.
Answer:
TNF-alpha is expressed as a homotrimer that exerts its activities through binding to two types of receptors: TNFR1 and TNFR2, which are transmembrane glycoproteins characterized by having an extracellular domain with 4 cysteine-rich domains (CRD 1-4) , each with 3 cysteinecysteine disulfide bonds.
Explanation:
TNF-alpha (Tumor Necrosis Factor), which has the characteristic of being a paracrine signaling ligand, is a pleiotropic cytokine that functions as a mediator of immune regulation, the inflammatory response and apoptosis in some cell types. Receptors in this family are involved, with some exceptions, in juxtacrine signaling; that is, both the ligand and the receptor are membrane proteins with extracellular domains through which signaling is established. The cellular responses promoted by TNF are initiated by its interaction with two different types of cell receptors, the type I receptor (55 kDa) and the type II receptor (75 kDa). Both types of receptors are part of the TNF receptor family, members of which include Fas antigen (apoptosis inducer, also called Apo-1 or CD95), CD27 (T-cell activation antigen), CD30 (lymphoma marker Hodgkin) and CD40 (B-cell antigen), which share the characteristic of cysteine-rich sequences in their extracellular domains. This family of cytokines generate cellular responses that include differentiation, proliferation, activation of NFκB and cell death, promoting the aggregation of receptor monomers, that is, they have a transmembrane domain that participates in the solubilization of the receptor and a domain of intracellular death that is involved in signal transduction. The binding of TNF to TNF-R1 induces a signaling cascade through its intracellular death domain, which subsequently leads to the activation of complex I (or inflammatory) of NFkB and proceeds to the transcription of anti-apoptotic genes, pro- inflammatory diseases and apoptosis complex II (caspases).
Answer:
<h2>Muscular System.... off course</h2>
Natural selection<span> acts upon two major sources of genetic variation: </span>mutations<span> and</span>recombination<span> of </span>genes<span> through sexual </span>reproduction<span>. Most </span>mutations<span> do not affect the reproductive fitness of individuals -- some may be beneficial, some may be harmful, and </span>many<span> may be neutral. </span>Mutation rates<span> per gene are generally low</span>
Answer:
Hello!!! Princess Sakura here ^^
Explanation:
True because the xylem transports water from the roots to the rest of the plant's body above ground and can only move up, whereas the phloem transports organic compounds both up and down the plant.
