Which enzyme is responsible for relieving the torsional stress caused by dna unwinding in the process of dna replication?
1 answer:
The process of DNA replication leads to the build up of torsional stress in the synthesised DNA helix. This torsional stress is due to the presence of tighter turns within the newly synthesised DNA helix. The DNA replication machinery then recruits the DNA topoisomerase enzyme to release the torsional stress by cleaving the synthesised DNA strands, followed by their ligation.
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