Sickel cell anemia is an inherited disease that is due to a base substitution mutation in a gene.
If you want to know how it looks outside of your body then that's when your fingers are wrinkled like if you soak your hands in water or take a long shower or bath that could be when water is entering your cells.
Hope this helps!
Answer:
Famine.
Explanation:
Famine, a shortage of water or food, will often result in a significant population decrease.
