The most signficant impact of the anti-federalists on the Constitution was the implementation of the Bill of Rights.
Anti-federalists were concerned that the new US Constitution gave too much power to the federal government. Anti-federalists argued that a strong central (aka federal) government would result in tyranny, just like it did when America was still part of the British empire. This is why the anti-federalists wanted a list of rights that all American citizens can possess. This list of rights would check the power of the federal government and prevent the government from restricting the rights of citizens.
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Answer:
Europeans explored and claimed that more and more land was there. They had to make relations with people who were already in the Americas and try to find a way to conquer them and claim that land theirs.
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They disliked it with a passion and openly opposed it, often being in wars with western forces. From China who was in war with Britain over colonization, to Korea, Vietnam, Cambodia, Laos, and many others.