If the specific sequence of nitrogenous bases in DNA is changed, this will in turn change the sequence of nitrogenous bases in the mRNA (after transcription). During the process of translation, different amino acids will be incorporated in a different sequence due to the different mRNA codons in the mRNA strand. This would most likely result in a non-functionalprotein or a differentproteinwithotherchemicalpropertiesthan the one specified in the original DNA sequence.