The reason why Native Americans (and any group of people, for that matter) who practiced agriculture were more likely than hunter gatherers to establish homes is because they had a surplus of food, which meant that other people who did not farm were free to establish trade and develop new skills that led to a community atmosphere.
He’s trying to say that it would be almost impossible to continue their journey without having an important part of his mind outwards and shared with the world
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This made it difficult for people to cross from one side of the peninsula to the other.