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Lorico [155]
3 years ago
11

Researchers can manipulate the genes of a mouse so that a single gene in a single tissue either produces an inactive protein (a

knockout mouse) or produces a protein that is always (constitutively) active. What effects on metabolism would you predict for mice with these genetic changes?
Biology
1 answer:
s2008m [1.1K]3 years ago
4 0

Answer:

1) The genetic changes can lead to a reduction in the capacity of the mice to move glycogen at its branches points and lowers blood glucose levels between meals.

2) Genetic changed can lead to a decrease in the capacity to lower blood glucose due to the knock out of the hexokinase gene leading to elevated levels in the bloodstream.

(c) A knockout of FBPase2 will result in elevated levels of fructose-2,6-bisphosphate in

liver favoring the glycolytic pathway and inhibiting gluconeogenesis by the decrease of fructose 1,6-

bisphosphatase-1 activity

(d) An active FBPase-2 will now favor gluconeogenesis and this inhibits glycolysis. I.e. a decrease in PFK-1 activity while increasing FBPase-1 activity simultaneously.

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The stomach,small intestine, esophagus or liver secretes special enzymes that help the stomach digest fats.
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Explanation:

<u>The stomach </u>

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Further Explanation:

Food is chemically and mechanically broken down into smaller particles. In the stomach the enzyme gastric lipase acts on lipids, breaking them up into their components. Phospholipids, bile acids, bilirubin, and cholesterol are combined into bile in the liver, which when secreted into the duodenum of the small intestine; this comes from its storage site, the gall bladder, and functions as an emulsifier or as a detergent.

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Item 10
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Answer A or answer C
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