An inhibition of mRNA syntheis will not effect the liver cells, but the liver cells will die because it causing the liver stop functioning (the death of liver cells). Cell are changes DNA to mRNA and translated into cystol and proteins. The proteins in liver cells performs various functions like it helps to detoxification and processing to fulfills liver's function.
If these proteins are not present in these cell or when the protein is damaged then, the cells will die as will the liver itself.
The liver cells will die causing the liver to stop functioning when protein gets damaged or destroyed. When protein gets damaged there will be no more new proteins that will be produced therefore, the absence of mRNA is equivalent to the non-production of proteins in cells.
