In diseases, similar patterns of mutations in harmless genes may possibly be a cause or an effect of the disease. To investigate if it is a cause, it is worth looking into the proteins synthesized by the gene and whether it’s structure or functionality is affected by the pattern observed. It is also worth looking into the downstream effects possibly caused by the pattern in the gene. The gene may encode a non coding region which could affect post transcriptional splicing for example.
Answer:
By preventing the synthesis of DNA halting cell growth.
Explanation:
Fluorouracil and methotraxate prevent the synthesis of the neucleoside Thymidine thus preventing DNA replication and elongation. Methotraxate has a structure analogous to Folic acid which is important for thymidine synthesis. Thus, it acts as a competitive inhibitor on dihdrofolate reductase an enzyme that is essential for tetrahydrofolate formation, a folic acid derivative.
Fluorouracil acts by inhibiting thymidylate synthase which catalyses an essential step in Thymidine synthesis.
The answer is a black mamba.
The black mamba is predator typically found in central Africa. Not only that its scales are black but also an interior of its mouth. It moves very quickly and at any sudden movement, it is ready to slay its opponents through a rapid application of venomous strikes. <span>Its venom is highly toxic and it could kill a man for 10-15 hours after the bite if antivenom is not applied.</span>
<span>When the molecules in a solid are heated (heat is the same as molecular movement) they move faster due to the energy gain and when they have enough energy they can overcome the attraction they have between each other and break their bonds to form a liquid, and if heated further a gas.</span>
The process of respiration system would not function well if the lungs was made up of only one big alveoli.
<u>Explanation:</u>
The main role of alveoli is to help the lungs to breath, for ventilation, diffusion and perfusion. The process of respiration system would not function well if the lungs was made up of only one big alveoli.
Alveoli are tiny to help the flow of oxygen and carbon dioxide, it helps the oxygen flow into the lungs and remove the carbon dioxide. If the alveoli is just one and big, then it would be hard to flow the oxygen through lungs and remove the carbon dioxide.
Therefore, it is good to have many tiny alveoli than one big one or the rib cage that protect the lungs could go through some damages.