Theory I believe Hope it helps
Answer: B
WHY?
Deletion mutation may cause a shift of base sequence, causing the reading frames for base sequence to change during translation. This may affect the type of amino acid it the original base sequence codes for, resulting in a change in amino acid sequence in the polypeptide translated. Therefore, affecting the whole protein itself. There may be wrong amino acids that prevents vital bonds like disulfide bridges to form, resulting in a huge change in 3 dimensional conformation of the protein. A point mutation may result in a gene sequence being edited. However, only the target sequence is being mutated. The rest of the gene sequences are left untouched. Therefore, the impact is localised. This ensures that even though a few wrong amino acids may be in the polyleptide, most of the bonds that are crucial for the correct 3 dimensional conformation is still present, therefore, lesser defects will be resulted due to point mutation as compared to deletion mutation.
<span>Atherosclerotic
peripheral vascular disease is symptomatic with at least 50% occlusion. The primary peripheral symptom, due to ischemia, is calf pain.
</span>This disease is a form of arterial insufficiency, which means that blood circulation through the arteries is decreased.<span>Other symptoms include painful cramping in the hip, thigh or calf muscles after certain activities, such as walking or climbing stairs (claudication)<span> and leg numbness or weakness.</span></span>
The phenomenon where one gene can modify the effect on the second gene is known as epistasis.
In genetics, epistasis is a phenomenon in which the effect of a gene mutation is determined by the presence or absence of mutations in one or more other genes, which are referred to as modifier genes. To put it another way, the genetic background in which the mutation appears determines its effect. It has long been acknowledged that epistasis, or interactions between genes, is fundamental to comprehending both the structure and function of genetic pathways and the evolutionary dynamics of complex genetic systems.
Learn more about Epistasis here:
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