The second plague pandemic in medieval Europe started with the Black Death epidemic of 1347–1353 and killed millions of people over a time span of four centuries. It is commonly thought that after its initial introduction from Asia, the disease persisted in Europe in rodent reservoirs until it eventually disappeared.
Answer: In the latest study, the researchers found outbreaks of plague from 1346 through 1837 which could be explained by changes in Asian weather. ... "When the climate subsequently becomes unfavorable, it facilitates the collapse of plague-infected rodent populations forcing their fleas to find alternative hosts.
