Colonists were forbidden to settle west of the apex (highest peak) of the Appalachian mountains.
Ben Cardin and Chris Van Hollen
Answer:
Portuguese explorer Prince Henry, known as the Navigator, was the first European to methodically explore Africa and the oceanic route to the Indies. From his residence in the Algarve region of southern Portugal, he directed successive expeditions to circumnavigate Africa and reach India.
Answer: Medieval doctors did not have a clue what caused disease. Most doctors still believed the Greek theory from Galen, a doctor during the Roman Empire, that you became ill when the 'Four Humours' - phlegm, black bile, yellow bile, blood - became unbalanced.