In 1854, the Missouri Compromise was repealed by the Kansas-Nebraska Act. Three years later the Missouri Compromise was declared unconstitutional by the Supreme Court in the Dred Scott decision, which ruled that Congress did not have the authority to prohibit slavery in the territories.
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One would be the rising greediness and not to mention demand for goods and another would be rebels were around during this time because of the Civil war starting soon.
The two executive powers that the constitution delegates to the senate are the power to confirm presidential appointments and the power "advice and give consent on treaties" formulated by the President.
