Answer: from the tea to the air
<span>Rattlesnakes would eat a prairie dog if they could catch it. However, if a rattlesnake approached a prairie dog colony, the prairie dog's "sentinels" would alert the rest of them, and they would hide in their holes. A rattlesnake could fit into the holes, but I don't think that snakes usually actively seek prey (they act more like a trap, waiting for prey to come to them). </span>
Answer:
by designing a drug with steric effects on BCR-ABL1
Explanation:
Chronic myeloid leukemia (CML) is a type of cancer that affects the bone marrow and blood cells. CML is characterized by the formation of the Philadelphia chromosome, a product of a reciprocal translocation between chromosomes 9 and 22. As a consequence of this translocation, an oncoprotein tyrosine kinase called BCR-ABL1 is formed. This protein (BCR-ABL1) is responsible for 95% of all CMLs. In this case, it is possible to inhibit BCR-ABL1 (and thus inhibit CML cell proliferation) by using a kinase inhibitor. Kinase inhibitors are drugs that inhibit kinase function by preferentially binding to the inactive conformation of the target enzyme. These proteins are used to treat cancer by blocking a functional site on the kinase, thereby inhibiting its function. Moreover, it is known that steric effects alter the mode and rate by which a drug interacts with a given target. In this case, a small molecule with steric effects on BCR-ABL1, i.e., capable of altering the shape (conformation) and reactivity of BCR-ABL1, might also be used to selectively inhibit BCR-ABL1.
Answer:
d. to produce the soil
Explanation:
pioneer species produce soil so other species less hardy can grow
D.) people may disagree in their interpretations of instant data.