Answer:
In this study, we tested the effects of NEAA-deprived diets and checkpoint inhibitor anti-PD-1 and anti-PD-L1 in colon cancer using syngeneic mouse model (Balb/c) bearing tumors of mouse colorectal cancer cell line CT-26. Three diets were tested, including a natural rodent diet Teklad ENVIGO Global 16% Protein Rodent Diet (control 1), a formulated NEAA-complete diet COMPLETE (control 2, using amino acid mix in place of protein), and a formulated NEAA-deprived diet FTN203 (treatment, using amino acid mix in place of protein). Both COMPLETE and FTN203 have the same nutritional structures, contain 17% w/w protein equivalent, and are isocaloric. After tumor size-based randomization, these diets were provided to mice ad libitum throughout the whole test. Each of these diets was used alone or combined with anti-PD-1 antibody (i.p., twice per week for 2 weeks) or anti-PD-L1 antibody (i.v., twice per week for 2 weeks).
Explanation:
1. Using washers, the volume is given by the integral


We're using washers whose centers depend on the value of
, hence we integrate with respect to
2. The area of the given region is given by the integral

To compute the integral, first consider the substitution
, or
so that
. Then
and
, so the integral is equivalently

Integrate by parts, taking


so that

and
, so the area is

For the remaining integral, substitute
, so that
. Then
and
:

(notice that the integral is improper)


Fine-grained, dark-colored mafic minerals
Answer:
a.)
Operant conditioning -
It is a type of learning in which a person learns from consequences ( which may be positive or negative ) that follows person's behavior.
The procedures which encourage the person to do the things the same way he/ she used to do are called reinforcement,
The procedures which discourage the person to do the things the same way he/ she used to do are called punishment.
b.)
Strategies Jim and Kelly could use to encourage or discourage Ryan's behaviors :
Positive Reinforcement -
If Ryan eats without dropping off his food from the plate , it will be encouraging for him if Jim and Kelly appreciate him or buy gifts for him.
Negative Reinforcement -
If Ryan eats without dropping off his food from the plate , it will be encouraging for him if Jim and Kelly should avoid that behavior due to which Ryan is not learning the table manners.
For example - The scolding of Jim or Kelly when Ryan's is dropping off the food on the floor.
Positive Punishments -
If Ryan eats with dropping off his food from the plate , it will be encouraging for him if Jim and Kelly will add some consequences which Ryan will hate.
For example - If Ryan is eating with dropping off the food and Jim or Kelly yells at Ryan for his bad behavior.
Negative Punishments -
If Ryan eats with dropping off his food from the plate , it will be discouraging for him if Jim and Kelly removing any good thing in which Ryan is comfortable.
For example - Ryan's watching TV time reduced or taken away his toys.
Answer:
The corona pandemic is harming health, social and material well-being of children worldwide, with the poorest children, including homeless children and children in detention, hit hardest. School closures, social distancing and confinement increase the risk of poor nutrition among children, their exposure to domestic violence, increase their anxiety and stress, and reduce access to vital family and care services. Widespread digitalisation mitigates the education loss caused by school-closures, but the poorest children are least likely to live in good home-learning environments with internet connection. Furthermore, increased unsupervised on-line internet use has magnified issues around sexual exploitation and cyber-bullying.
Immediate government measures need to ensure that children have access to good food, receive protection against child abuse and neglect, have continued access to child physical and mental health services, and can navigate safely on the internet. Policies also need to support parental employment since it is key to fighting child poverty.
Explanation:
<h3> I hope it will help you</h3>
<h3><em>please</em><em> make</em><em> me</em><em> brainlest</em></h3>
<h2><em> </em><em> </em><em> </em><em> </em><em> </em><em> </em>THANK U</h2>