Answer:
It affected the Americans positively long terms, but negatively in the early times of the exchange.
Explanation:
The Columbian Exchange greatly affected America, bringing destructive diseases that depopulated the Americans but did distribute a wide variety of new crops and livestock throughout the American farm industry. In the long term, this rather increased the human population but still very profoundly affected the Americans.
The Thirteen original colonies were Founded by Britain, but eventually would break free of British rule and become their very own country which is known as The United States Of America.
Those who opposed giving the federal government more power than the states were known as the "Anti-Federalists", since they did not want to ratify the Constitution, which would have done this.
They were trying to accomplish better working conditions and better pay for the field workers.