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ahrayia [7]
3 years ago
10

Chronic myeloid leukemia (CML) is a genetic disorder associated with the Philadelphia chromosome. The Philadelphia chromosome is

a mutation in chromosome 22. Part of chromosome 22 is exchanged with part of chromosome 9, bringing together two genes on chromosome 22 and causing a malignancy. What type of mutation occurs in the Philadelphia chromosome?
A: duplication
B: Insertion
C.Inversion
D. substitution
E.translocation
Biology
2 answers:
ivolga24 [154]3 years ago
7 0
E; translocation, which is a chromosomal rearrangement in which a part of genetic material from one chromosome becomes heritably (genetically) tied to another chromosome.*

Sources:
*Definition of "Translocation" (Paraphrase):
http://www.dictionary.com/browse/translocation?s=t

The Philadelphia Chromosome:
https://www.medicinenet.com/script/main/art.asp?articlekey=4870
Elena L [17]3 years ago
5 0

Answer:

E.translocation

Explanation:

The chromosomal disorder CML is caused by reciprocal translocation between chromosome 9 and chromosome 22, in which rearrangement of chromosomes takes place.

Due to this rearrangement, part of chromosome 9 having ABL1 gene gets fused with part of chromosome 22 having BCR gene and resulting chromosome is known as Philadelphia chromosome.

ABL1-BCR fusion gene represents an oncogene that codes for a mutated protein that leads to unregulated cell division and impaired DNA binding and can cause cancer.

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Match the steps in the cell cycle in the correct order
Tcecarenko [31]

Answer:

1. Chromosomes line up - metaphase

2. Cell growth - G1

3. Final preparations for division - G2

4. Chromosomes get pulled apart - anaphase

5. DNA replication - S

6. Chromosomes condense - prophase

7. Chromosomes uncoil and nucleus reforms - telophase

8. The cytoplasm and organelles divide, and now there are two identical cells - cytokinesis

Explanation:

There are four primary phases, or stages, in the cell cycle, which is a systematic process. Each stage has a goal that has to be achieved before moving on to the next. G1, S, G2, and mitosis are the stages.
There is growth during the G1 phase. A lot of protein is produced and water is pumped in, increasing the volume of the cell. The DNA is also examined at this time to see whether there has been any damage. The G1 phase precedes the S phase, therefore before going into S phase, the cell must make sure it has enough energy reserves.

The cell duplicates its DNA during the synthesis phase, also known as the S phase. DNA content doubles due to the duplication of all chromosomes. The compact state of DNA is created by proteins, which do not exist in and of themselves. Therefore, in order to ensure that the new DNA is properly packed when DNA is replicated, new packaging proteins must be produced. Histones are the proteins that house DNA. The production of new DNA is closely linked to the production of new histones.

A cell multiplies its organelles during the G2 phase. Right before the cells divide into two distinct cells during mitosis, the G2 phase occurs. There must be distinct functioning organelles in each daughter cell. Organelles like the golgi and endoplasmic reticulum are linked networks of sizable membrane pouches that may change size. Other organelles, including mitochondria and chloroplasts, are separate structures that must separate similarly to how cells do.

The process of physically dividing a cell into two daughter cells is called mitosis. Prophase, metaphase, anaphase, and telophase are its four basic stages. The nuclear membrane deteriorates as the chromosomes thicken during prophase. The center of the cell's chromosomes align during metaphase. One chromosome splits in half during anaphase, sending one half to either side. The telophase is characterized by the pinching together of the cell's centre to form two separate cells.

6 0
1 year ago
The part of an amino acid that contains nitrogen is called
Arada [10]
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6 0
3 years ago
A well supported testable explanation of phenomena that have occurred in the natural world is called
gtnhenbr [62]
For the answer to the question above, the answer is simply a "Scientific Theory"
<span>it is a well-substantiated and well-presented explanation of the natural world, it is based on repeatedly confirmed through observation and experiment of the said phenomena. These are not the wild guess but reliable facts of the real world events.</span>
3 0
3 years ago
A person driving a car applies the brakes.This produces friction, which stops the car.Into which type of energy is the mechanica
dalvyx [7]

When a car stops it converts its kinetic energy into heat energy as the breaks are applied the engine gets heated along with breaks and tiers .

5 0
3 years ago
Read 2 more answers
Plz help me- I will mark brainliest
zmey [24]

1. Skeletal but I’m not entirely sure

2. Reproductive

3.Digestive

4. Nervous

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6. Circulatory

7. Muscular but I’m not entirely sure

8. Excretory

9. Immune

10. Skeletal

11. Respiratory

5 0
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