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ahrayia [7]
3 years ago
10

Chronic myeloid leukemia (CML) is a genetic disorder associated with the Philadelphia chromosome. The Philadelphia chromosome is

a mutation in chromosome 22. Part of chromosome 22 is exchanged with part of chromosome 9, bringing together two genes on chromosome 22 and causing a malignancy. What type of mutation occurs in the Philadelphia chromosome?
A: duplication
B: Insertion
C.Inversion
D. substitution
E.translocation
Biology
2 answers:
ivolga24 [154]3 years ago
7 0
E; translocation, which is a chromosomal rearrangement in which a part of genetic material from one chromosome becomes heritably (genetically) tied to another chromosome.*

Sources:
*Definition of "Translocation" (Paraphrase):
http://www.dictionary.com/browse/translocation?s=t

The Philadelphia Chromosome:
https://www.medicinenet.com/script/main/art.asp?articlekey=4870
Elena L [17]3 years ago
5 0

Answer:

E.translocation

Explanation:

The chromosomal disorder CML is caused by reciprocal translocation between chromosome 9 and chromosome 22, in which rearrangement of chromosomes takes place.

Due to this rearrangement, part of chromosome 9 having ABL1 gene gets fused with part of chromosome 22 having BCR gene and resulting chromosome is known as Philadelphia chromosome.

ABL1-BCR fusion gene represents an oncogene that codes for a mutated protein that leads to unregulated cell division and impaired DNA binding and can cause cancer.

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Answer:

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Physical properties of water : Water is a colourless and tasteless liquid. The molecules of water have extensive hydrogen bonds resulting in unusual properties in the condensed form. This also leads to high melting and boiling points. As compared to other liquids, water has a higher specific heat, thermal conductivity, surface tension, dipole moment etc. These properties form the reason for its significance in the biosphere. Water is an excellent solvent and therefore it helps in the transportation of ions and molecules required for metabolism. It has a high latent heat of vaporization which helps in the regulation of body temperature

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Example:

Acidic Behaviour: H2O(l)+NH3(aq) ⇌ H3O+(aq)+NH+4(aq)

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During the process of photosynthesis, water is oxidized to O2. As water can be oxidized and reduced, it is very useful in redox reactions.

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Explanation:

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