The answer is A, or By underlining or italicizing it. Doing so draws eye-coordinated attention and emits a connotation that the word is significant to something more overlying than what is said.
You can eliminate C right away, which leaves you with A, B, and D. Personally, I would choose B and D. When choosing paths in life, its often important to make tough decisions. And these choices sometimes are dependent on your future, making the answer B and D.
Annoying
Beautiful
Carefully
Answer: mice is the standard form