Answer:the the threat of disease
Explanation:
<span>The resisted because they did not respect their culture so Pope lead his people, (The Natives) and rebelled against the Spanish.</span>
Because Columbus though that he had traveled across the sea and landed in India. He didn’t know the concept of America so he called them Indians
Answer: D They brought great wealth to Spain
Explanation: They made Spain a colony of Portugal. They opened the fur trade with American Indians. so it has to be D