Answer: NO, the size of the particles does not interfere with the renal circulatory volume, but it does with the glomerular filtration process.
Explanation:
Glomerular filtration has mechanisms to precisely control the volume of glomerular circulation, thus there are intrinsic mechanisms such as renal self-regulation in which the kidney adjusts the dilation or construction of the afferent arterioles and extrinsic mechanisms such as neuronal control performed by the nervous system and Hormonal control, such as the renin-angiotensin-aldosterone system, which regulates blood pressure and fluid balance, particles in the blood that are too large can affect the renal system, but their ionic charge and size can be reduced it passes through the tubules of the nephron into the urine, which prevents them from leaking, however, this is not an impediment for them to circulate in the renal blood system.
