Answer:
In this study, we tested the effects of NEAA-deprived diets and checkpoint inhibitor anti-PD-1 and anti-PD-L1 in colon cancer using syngeneic mouse model (Balb/c) bearing tumors of mouse colorectal cancer cell line CT-26. Three diets were tested, including a natural rodent diet Teklad ENVIGO Global 16% Protein Rodent Diet (control 1), a formulated NEAA-complete diet COMPLETE (control 2, using amino acid mix in place of protein), and a formulated NEAA-deprived diet FTN203 (treatment, using amino acid mix in place of protein). Both COMPLETE and FTN203 have the same nutritional structures, contain 17% w/w protein equivalent, and are isocaloric. After tumor size-based randomization, these diets were provided to mice ad libitum throughout the whole test. Each of these diets was used alone or combined with anti-PD-1 antibody (i.p., twice per week for 2 weeks) or anti-PD-L1 antibody (i.v., twice per week for 2 weeks).
Explanation:
Answer:
Playas
Explanation:
"A playa is a dry, vegetation-free, flat area at the lowest part of an undrained desert basin. It is a location where ephemeral lakes form during wet periods, and is underlain by stratified clay, silt, and sand, and commonly, soluble salts."
Answer:
The growth of inter-regional trade in luxury goods was encouraged by innovations in previously existing transportation and commercial technologies, including the caravanserai, forms of credit, and the development of money economies as well as the use of the compass, the astrolabe and larger ship designs.
Explanation:
Caravanserais, large guest houses for travelling merchants and their caravans, were dispersed along the land routes of the Silk Roads. ... By offering such an intercultural environment, caravanserai were important sites for the exchange of material culture, languages and ideas.
...of strict social stratification...
Answer: Southeast Asian City Model
Explanation: should help