Answer: Genetic engineering has many applications to medicine that include the manufacturing of drugs, creation of model animals that mimic human conditions and gene therapy.
Explanation:
ATP is not generated directly in the citric acid cycle. Instead, an intermediate is first generated by substrate-level phosphorylation. The intermediate is GTP.
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What is GTP?</h3>
- A purine nucleoside triphosphate is guanosine-5'-triphosphate.
- It serves as one of the components necessary for the creation of RNA during transcription.
- The main distinction between its structure and that of the guanosine nucleoside is the presence of phosphates on the ribose sugar of nucleotides like GTP.
- Also known as guanosine triphosphate, this energy-dense nucleotide is similar to ATP and is made up of guanine, ribose, and three phosphate groups.
- It is required for the creation of peptide bonds during protein synthesis.
- Adenine nitrogenous base, sugar ribose, and triphosphate make up ATP, a nucleoside triphosphate, whereas guanine nitrogenous base, sugar ribose, and triphosphate make up GTP.
- This is the main distinction between the two compounds.
- The alpha-guanosine subunit's diphosphate (GDP) is converted into guanosine triphosphate (GTP), and the GTP-bound alpha-subunit subsequently separates from the beta- and gamma-subunits.
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In some cases, massive destruction of red blood cells caused death. This drug-induced hemolytic anemia was shown 30 years later to be caused by a deficiency of glucose 6-phosphate dehydrogenase, the enzyme catalyzing the first step in the oxidative branch of the pentose phosphate pathway.
in short terms, glucose 6-phosphate dehydrogenase
