Answer:
This probably because they destroy a given character or give rise to a new one.
Explanation:
Alteration here are the permanent changes found in the DNA structure. And are totally inheritable. An example is the case of sickle cell anaemia and haemophilia. People with this anaemia trait hardly live and reproduce even though they do not show ill effects.
Therefore, this mutation alteration is harmful because they destroy a given character.
They might be deep inside
B. Histones is the correct answer.