In 1517, Martin Luther wrote a document attacking the Catholic Church of being corrupt by selling indulgences to pardon sin. This document was the "95 Theses". This document was the based on which was written the Protestant Reformation.
The Protestant Reformation divided the Catholic Europe, because Martin Luther, John Calvin and Henry VIII challenged papal authority to define Christian practice.
The most correct answer here would be the growing of crops nad the taming of animals by early hmans. The Neolithic revolution is often seen as the transition from hunter-gatherer societies to societies of agricultural production and husbandry.