Well if you were to ask me 1 is that sporulation can make lots of more plants but i dont know any disadvntages
Wouldn’t the answer just be C?
<span>Lafora disease is the most severe teenage-onset progressive epilepsy, a unique form of glycogenosis with perikaryal accumulation of an abnormal form of glycogen, and a neurodegenerative disorder exhibiting an unusual generalized organellar disintegration. The disease is caused by mutations of the EPM2A gene, which encodes two isoforms of the laforin protein tyrosine phosphatase, having alternate carboxyl termini, one localized in the cytoplasm (endoplasmic reticulum) and the other in the nucleus. To date, all documented disease mutations, including the knockout mouse model deletion, have been in the segment of the protein common to both isoforms. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the disease. In the present work, we identify six novel mutations, one of which, c.950insT (Q319fs), is the first mutation specific to the cytoplasmic laforin isoform, implicating this isoform in disease pathogenesis. To confirm this mutation's deleterious effect on laforin, we studied the resultant protein's subcellular localization and function and show a drastic reduction in its phosphatase activity, despite maintenance of its location at the endoplasmic reticulum.
I got my information from </span>https://www.ncbi.nlm.nih.gov/pubmed/14722920
<span>Since there is usually more than one codon for an amino acid, a mutation in the third base of a codon
will most likely not cause the wrong amino acid to be put into the chain. </span>
Answer:
In allosteric inhibition, a regulatory molecule binds to a location other than the active site, resulting in a change in enzyme shape that allows the active site to bind substrate.
Explanation:
Allosteric regulation of an enzyme can be positive or negative, but it always involves effector molecules that bind to non-active site of the enzyme and change its conformation. That site of binding is called allosteric or regulatory site. If the enzyme activity is enhanced effector molecule is called allosteric activator but if the activity is decreased effector molecules are allosteric inhibitors.
