Question

Read the quotation from the Declaration of Independence. “[The king] has excited domestic insurrections amongst us, and has endeavored to bring on the inhabitants of our frontiers, the merciless Indian Savages, whose known rule of warfare, is an undistinguished destruction of all ages, sexes and conditions.” Which best describes the colonists' attitude toward American Indians? fearful and mistrusting sad and resigned optimistic but wary empathetic and understanding

Answer 1

 fearful and mistrusting

The words used to describe the way Native Americans carry out their 'warfare' in this passage are "merciless", "insurrections", and "destruction". It says that their method is to kill without thinking about age, gender, or condition, which is information that inspires fear and mistrust in the natives. 

Answer 2

The answer is fearful and mistrusting.