Among the main characteristics of Rafael Sanzio's works are the development of techniques based on highlighting the lights, simple and flat backgrounds, in addition to imprinting in his works human expressions in contrast with religious figures.
The main features of Leonardo da Vinci's paintings are the use of perspective artistic technique, the use of near reality colors, perfect human figures, religious themes, the use of mathematics in artistic calculations, centralized main images, background landscapes, human figures with Feeling expressions, artistic detail.