<span>achieve a therapeutic objective (cure disease, mitigate symptoms etc.)
minimize toxicity
minimize difficulty of administration
identify dosing regimens</span>List the goals of drug therapytherapeutic window/rangethe plasma concentration range that is effective and safe in treating specific diseasestrue(T,F): The therapeutic response is dependent on drug achieving an adequate plasma concentrationmultiple doses________ are given to stay in the therapeutic windowvolume of distribution (V)<span>an important indicator of the extent of drug distribution into body fluids and tissues
relates the amount of drug in the body to the measured concentration in the plasma
it is the volume required to account for all of the drug in the body if the concentration in all tissues is the same as the plasma tissue.</span>clearancethe process of removing a drug from plasma (expressed as volume of plasma per a given unit of time)true(T,F): Clearance indicates the volume of plasma (or blood) from which the drug is completely removed, or cleared, in a given time period.half-life<span>volume of distribution and clearance influences the _______ of a drug.
Dosing regimen: How often?</span>oral bioavailability<span>clearance and absorption influences the ________ of a drug
Dosing regimen: How much?</span>steady statethe amount of drug administered is equal to the amount of drug eliminated within one dosing interval resulting in a plateau or constant serum drug levelshortDrugs with a _____ half-life reach steady state rapidlylongDrugs with a ____ half-life take days to weeks to reach steady statetherapeutic windowA steady state is desired within the _________half-lifethe time necessary for the concentration of drug in the plasma to decrease by one-half (50%)about 5How many half-lives are required to reach steady state?loading dosesoften administered at the initiation of an infusion to achieve an immediate therapeutic plasma concentration of the drug (allows rapid achievement of therapeutic serum)true(T,F): The same loading dose is used regardless of metabolism/elimination dysfunction
White blood cells are an important component of your blood system, which is also made up of red blood cells, platelets, and plasma.
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Although your white blood cells account for only about 1% of your blood, their impact is significant. White blood cells, also called leukocytes, are essential for good health and protection against illness and disease.
The overall trip is 15 min for the 6 miles. Plugging that into the equation for Average velocity you get 6m/15min. The answer is asking for m/h. So we know there are 60 minutes in 1 hour. You cross multiply 6m/15min with 60min/1h and get 360m/15h and can reduce it to 24m/h.
Answer:
Apply ice also the individual should not be walking.
Explanation:
An open fracture happens when a broken bone cracks under the skin. This is a severe injury and needs immediate first aid approach. The two main hazards of open fractures are infected and bleeding. Broken bones are exposed to the disease, so if they are presented to the conditions there is a notable risk of forming a bone infection. These plaques can begin to loss of life or limb.