Answer:
Results
We systematically analyze and compare how different modelling methodologies can be used to describe translation. We define various statistically equivalent codon-based simulation algorithms and analyze the importance of the update rule in determining the steady state, an aspect often neglected. Then a novel probabilistic Boolean network (PBN) model is proposed for modelling translation, which enjoys an exact numerical solution. This solution matches those of numerical simulation from other methods and acts as a complementary tool to analytical approximations and simulations. The advantages and limitations of various codon-based models are compared, and illustrated by examples with real biological complexities such as slow codons, premature termination and feedback regulation. Our studies reveal that while different models gives broadly similiar trends in many cases, important differences also arise and can be clearly seen, in the dependence of the translation rate on different parameters. Furthermore, the update rule affects the steady state solution.
Conclusions
The codon-based models are based on different levels of abstraction. Our analysis suggests that a multiple model approach to understanding translation allows one to ascertain which aspects of the conclusions are robust with respect to the choice of modelling methodology, and when (and why) important differences may arise. This approach also allows for an optimal use of analysis tools, which is especially important when additional complexities or regulatory mechanisms are included. This approach can provide a robust platform for dissecting translation, and results in an improved predictive framework for applications in systems and synthetic biology.
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Answer:
i dont know but i think both
Explanation:
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It- damages the DNA in skin cells and produces genetic defects that can lead to cancer.
Answer: By losing its two outermost electron
Explanation:
Calcium is a element that belongs to group 2 in the periodic table. It has an atomic number of 20, and an electronic configuration of 2, 8, 8, 2.
Hence, to form an octet structure, it gives off its two electrons as shown below:
Ca <----> Ca2+ + 2e-
Thus, by losing its two outermost electrons, a positively charged calcium ion (Ca2+) is formed
Answer:
Genotype of the offspring: 4 CC is equal ratio. Phenotype will be 4 yellow cocoons. (CC)
Explanation:
The inheritance of cocoon color in silkworm is a classic illustration of mono-hybrid cross. Mono-hybrid because the color of cocoon is determined by single gene. The yellow color of cocoon is dominant and the homozygous dominant allele is represented as CC. While the white color of cocoon is represented as cc homozygous recessive alleles. As per punnett square method the offspring cocoon color will follow the above mentioned genotypic and phenotypic ratios respectively.
