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Inoculation is a set of methods of artificially inducing immunity against various infectious diseases. The practice originated in the East before being imported to the Western world. The terms inoculation, vaccination, and immunization are often used synonymously, but there are some important differences between them.
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The fur trade resulted in many long term effects that negatively impacted Native people throughout North America, such as starvation due to severely depleted food resources, dependence on European and Anglo-American goods, and negative impacts from the introduction of alcohol-which was often exchanged for furs.
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