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dolphi86 [110]
3 years ago
14

nvestigator A conducts research on emphysema using biospecimens from human subjects. The consent form indicates that the researc

h will focus exclusively on emphysema. Investigator B wishes to use the biospecimens for research on lung cancer. Can Investigator B use the specimens for cancer research without re-consent if the specimens are de-identified?
Biology
1 answer:
melamori03 [73]3 years ago
6 0

Answer:

The correct answer is: Yes.

Explanation:

  • Conducting research on human subjects and specimens require the research organisation to obtain prior permission or consent from the person on whose specimen the research is being conducted.
  • These ethical guidelines provided by the ethical committee need to be followed by all the research organisations and scientists.
  • De-identification of biological specimen refers to the non-revelation of identity and preservation of the confidentiality of the person from whom the biological specimen is derived. The person from whom the biological specimen is obtained is made anonymous.
  • According to the question, Investigator A obtained the biological specimen from human subjects for conducting research on emphysema.
  • Under conditions of de-identification of the specimen, the specimen can be used by the Investigator B for performing research on lung cancer without the necessity for a re-consent.
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Answer:

The answer is explained below

Explanation:

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6 0
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Boris Magasanik collected data on the proportion of each base in RNA from different species. To compare the relative amount of e
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Answer:

The nucleic acid is a macromolecule present in living systems in the form of either DNA or RNA, whose molecule consists of many nucleotides which are linked with each other to form long chains. The presence of DNA or RNA in an individual promotes continuity of life. The variability and complexity of nucleic acid are dependent on its constituent molecules as, sugar, a phosphate group, and a nitrogenous base. However, two monocyclic nitrogenous bases were classified purines (adenine:A, guanine:G) and pyrimidines (thymine:T, cytosine:C, and uracil:U).

In addition, RNA is a single-stranded structure which differs from DNA in two aspects, the sugar content of RNA is ribose, and pyrimidine base uracil replaces the thymine base of DNA. A ratio between two strands of DNA can be calculated by using Chargrff's rule which states that "DNA from any cell of all organisms possess a 1:1 ratio (base Pair Rule) of pyrimidine and purine bases'.

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Presence of single strand in RNA does not follow chargaff's rule and alters the purine: pyrimidine ratio. The above ratio of each base in the given information is not equal, due to which the ratio of purines to pyrimidines is different. The ratio of DNA and RNA is not equal because DNA has its complementary DNA strand. However, bases in RNA might vary due to its single-strandedness property, but its ratio is dependent on the species.

Therefore, it can be concluded that the ratio of purines to pyrimidines is dependent on the species due to its genetic makeup. Hence, option (c) is correct.

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