The easy experimental answer to this question is 264 hours<span> (</span>about 11 days<span>). In 1965, Randy Gardner, a 17-year-old high school student, set this apparent world-record for a science fair. Several other normal research subjects have remained awake for eight to 10 days in carefully monitored experiments.</span>
Large dose of folate increase the symptom of vitamin B12 deficiency . the vitamin B12 deficiency can lead to permanent damage of the spinal cord nerves and brain.
It can cause severe birth defects which is called neural tube defects. this defects include spinal, pifida . folate deficiency can also increase your chance of placental abrupt ion is a condition in which placental separate from uterus.
High dose of folate typically be remedied by taking supplement of both folic acid and vitamin B12. vitamin B12 works closely with vitamin B9 also called folic and folate acid which is help to make red blood cells and iron work better in our body.
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Guessing it’s D. Hope this was helpful!
