Question

The initial dose of theophylline for an adult is 0.8 mg/kg/hr for 12 hours. how many ml of an iv solution containing 800 mg per 100 ml would be required for a 250 lb. male over this 12 hour period?

Answer 1

If the patient weight is 250 lb and the doses are 0.8mg/kg/hour for 12 hours, then the total amount of theophylline needed would be:
250lb * 0.453592kg/lb* 0.8mg/kg/hr * 12hr= 1088.6208mg

If the solution contains 800mg of theophylline for 100ml volume, then the volume needed would be: 1088.62 mg / (800mg/100ml)= 136.07ml