The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein. This alteration occurs during translation because ribosomes read the mRNA strand in terms of codons, or groups of three nucleotides. These groups are called the reading frame.
Ionic bonds result when electrons are tranfered between atoms. Covalent bonds result when valence electrons are shared between atoms. You should be able to identify whether an ionic or covalent bond is being formed between atoms.
That is a chemical change or reaction.