Just as Act III ends, right after Antony's funeral speech, Rome erupts into a chaotic, mob-led brawl. The people have been so inflamed by Antony's speech and the murder of Caesar, that chaos reigns and the country is on the brink of a civil war.
Act IV, by contrast, opens in what appears to be a calm and controlled meeting of the three men who will become Rome's second triumvirate of rulers: Marc Antony, Octavius.