Answer:
But this prosperity came at a cost, gobbling up the lands of Native Americans in the West and the labor of enslaved people in the South. ... The rise of political parties and the era of Jefferson ... The presidency of Andrew Jackson ... The War of 1812 was very unpopular in New England because it disproportionately affected ...
Explanation:
Hopefully this is the right answer! Sorry if it's wrong.
The smallpox epidemic.
The millitary invasion was devastating but not to the extent of smallpox.
The Jesuits did not really devastate the New World.
Enslavement for sugar plantations mostly occurred with Africans.
Smallpox, brought in by the Columbian Exchange, had a widespread impact that killed a large portion of natives in the Americas.
So the Smallpox epidemic is the answer.
Im not sure... Im answering every question so sorry for no answer but ife been trying to figure out the same thing